I’m not really sure what the RE in the title of this movie is supposed to imply. I don’t think it’s supposed to imply that it’s a statement in response of the Cyborg future of it all – whilst director Kamiyama has a background in GitS:SAC, this isn’t a movie about life, politics and terrorism in the all-connected robot future. In fact, the robotic nature of the movies protagonists only really serves as an excuse to give them all cool superpowers.
In other ways, it could perhaps be seen as indicating that the movie is in more direct response to the franchise as a whole – as Kamiyama himself put it after the movie, there’s been a big shadow cast over the property in terms of a final story, incomplete due to the original author Ishinomoris’ death, which has left the property in a place from which it has been difficult to continue or reinvent.
Or it could just start for Religious Education. Or exposition. That’d work.